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| 카탈로그 번호 | VK564054 | ||||||||
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| 설명 |
Anti-PEDV S1/Spike glycoprotein 1 Polyclonal Antibody (VK564054) is a rabbit polyclonal antibody detecting Spike glycoprotein in ELISA, IHC, WB.
Highlights
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| 종 반응성 | Porcine epidemic diarrhea virus (PEDV) | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant PEDV S1/Spike glycoprotein 1 (Gln21-Glu496). | ||||||||
| 테스트된 응용 분야 | WB | ||||||||
| 타겟 | Spike glycoprotein, S glycoprotein, E2, Peplomer protein, S, Porcine epidemic diarrhea virus, PEDV | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | S0AP48 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Spike glycoprotein (S1/Spike glycoprotein 1) is a ~151 kDa protein. S1 region attaches the virion to the cell membrane by interacting with the host receptor, initiating the infection. Binding to the receptor probably induces conformational changes in the S glycoprotein unmasking the fusion peptide of S2 region and activating membranes fusion. S2 region belongs to the class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. | ||||||||
| 참고사항 | For research use only. |
Western blot analysis was performed using anti-S1 polyclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant PEDV S1/Spike glycoprotein 1 (Catalog No: VK564012)
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