

| 카탈로그 번호 | HW829014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-PHB Polyclonal Antibody (HW829014) is a rabbit polyclonal antibody detecting PHB in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
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| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human PHB (Lys177-Gln272). | ||||||||
| 타겟 | Prohibitin, PHB, PHB1 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P35232 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Prohibitin 1 (PHB) is a ~29 kDa protein. Protein with pleiotropic attributes mediated in a cell-compartment- and tissue-specific manner, which include the plasma membrane-associated cell signaling functions, mitochondrial chaperone, and transcriptional co-regulator of transcription factors in the nucleus. Plays a role in adipose tissue and glucose homeostasis in a sex-specific manner. Contributes to pulmonary vascular remodeling by accelerating proliferation of pulmonary arterial smooth muscle cells. 1. Coates, PJ. et al. (2001) Experimental cell research 265, 262-73. PMID: 11302691 2. Strub, GM. et al. (2011) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 25, 600-12. PMID: 20959514 3. Wei, Y. et al. (2017) Cell 168, 224-238.e10. PMID: 28017329 4. Yoshinaka, T. et al. (2019) iScience 19, 1065-1078. PMID: 31522117 | ||||||||
| 참고사항 | For research use only. |
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