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| 카탈로그 번호 | HB851013 | ||||
|---|---|---|---|---|---|
| 종 반응성 | Human | ||||
| 응용 분야 | IHC, IP, WB | ||||
| 숙주 종 | Mouse | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG2a, kappa | ||||
| 클론 ID | SAA0304 | ||||
| 타겟 | cAMP-responsive element-binding protein 1, CREB-1, CREB1, Cyclic AMP-responsive element-binding protein 1 | ||||
| 내독소 수준 | Please contact with the lab for this information. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | P16220 | ||||
| RRID | Anti-Phospho-CREB1 (pS133) Antibody (SAA0304) (abinScience Cat# HB851013, RRID:AB_3725765) |
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| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 배경 | Cyclic AMP-responsive element-binding protein 1 (p-CREB1) is a ~35 kDa protein. Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-119 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells. Regulates the expression of apoptotic and inflammatory response factors in cardiomyocytes in response to ERFE-mediated activation of AKT signaling. 1. Conkright, MD. et al. (2003) Molecular cell 12, 413-23. PMID: 14536081 | ||||
| 참고사항 | For research use only. |
SDS-PAGE for Anti-Phospho-CREB1 (pS133) Antibody (SAA0304)
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