Anti-Phospho-KCNB1 (pS563) Recombinant Antibody (L83/11R) (RC581013)

Name: Anti-Phospho-KCNB1 (pS563) Recombinant Antibody (L83/11R)
Brand: abinScience
SKU: RC581013
Price: 191 USD
Availability: InStock

데이터시트 제품 공유 정보 복사

가격(USD):

사양:

50ug
100ug
1mg

수량:

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개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호

RC581013

종 반응성

Rat

응용 분야

IHC, IP, WB

숙주 종

Mouse

클론성

Monoclonal

이소타입

IgG2a, kappa

클론 ID

L83/11R

타겟

h-DRK1, Delayed rectifier potassium channel 1, Potassium voltage-gated channel subfamily B member 1, KCNB1, Voltage-gated potassium channel subunit Kv2.1, DRK1

내독소 수준

< 10 EU/mg

순도

>95% as determined by SDS-PAGE.

정제

Protein A/G purified from cell culture supernatant.

등록번호

P15387

형태

Liquid

저장 완충액

0.01M PBS pH 7.4.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

배경

Potassium voltage-gated channel subfamily B member 1 (p-KCNB1) is a ~95 kDa protein. Voltage-gated potassium channel that mediates transmembrane potassium transport in excitable membranes, primarily in the brain, but also in the pancreas and cardiovascular system. Contributes to the regulation of the action potential (AP) repolarization, duration and frequency of repetitive AP firing in neurons, muscle cells and endocrine cells and plays a role in homeostatic attenuation of electrical excitability throughout the brain. Also plays a role in the regulation of exocytosis independently of its electrical function. Forms tetrameric potassium-selective channels through which potassium ions pass in accordance with their electrochemical gradient. The channel alternates between opened and closed conformations in response to the voltage difference across the membrane.

1. Murakoshi, H. et al. (1999) The Journal of neuroscience : the official journal of the Society for Neuroscience 19, 1728-35. PMID: 10024359

2. Du, J. et al. (2000) The Journal of physiology 522 Pt 1, 19-31. PMID: 10618149

3. Malin, SA. et al. (2002) The Journal of neuroscience : the official journal of the Society for Neuroscience 22, 10094-105. PMID: 12451110

4. Guan, D. et al. (2007) The Journal of physiology 581, 941-60. PMID: 17379638

5. Mohapatra, DP. et al. (2009) Channels (Austin, Tex.) 3, 46-56. PMID: 19276663

6. Guan, D. et al. (2013) The Journal of physiology 591, 4807-25. PMID: 23878373

7. Feinshreiber, L. et al. (2010) Journal of cell science 123, 1940-7. PMID: 20484665

8. Ju, M. et al. (2003) The Journal of biological chemistry 278, 12769-78. PMID: 12560340

9. Taglialatela, M. et al. (1991) Molecular pharmacology 40, 299-307. PMID: 1875913

10. VanDongen, AM. et al. (1990) Neuron 5, 433-43. PMID: 2206531

참고사항

For research use only.

이미지

SDS-PAGE

SDS-PAGE for Anti-Phospho-KCNB1 (pS563) Antibody (L83/11R)

참고 문헌

데이터시트

Anti-Phospho-KCNB1 (pS563) Recombinant Antibody (L83/11R).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-Phospho-KCNB1 (pS563) Recombinant Antibody (L83/11R) (RC581013)

개요

이미지

참고 문헌

데이터시트

SDS

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