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| 카탈로그 번호 | VK078014 | ||||||||
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| 설명 |
Anti-Phosphoprotein Polyclonal Antibody (VK078014) is a rabbit polyclonal antibody detecting P phosphoprotein in ELISA, IHC, WB. Suitable for Nipah virus and Hendra virus.
Highlights
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| 종 반응성 | Nipah virus (NiV), Hendra virus (HeV) | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant nipah virus Phosphoprotein (Asp471-Gly580). | ||||||||
| 타겟 | P phosphoprotein, partial; P/V/W/C | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | O55778, Q9IK91 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Phosphoprotein is a ~78 kDa protein. Essential cofactor of the RNA polymerase L that plays a central role in the transcription and replication by forming the polymerase complex with RNA polymerase L and recruiting L to the genomic N-RNA template for RNA synthesis. Also plays a central role in the encapsidation of nascent RNA chains by forming the encapsidation complex with the nucleocapsid protein N (N-P complex). Acts as a chaperone for newly synthesized free N protein, so-called N0, allowing encapsidation of nascent RNA chains during replication. The nucleoprotein protein N prevents excessive phosphorylation of P, which leads to down-regulation of viral transcription/ replication. Participates, together with N, in the formation of viral factories (viroplasms), which are large inclusions in the host cytoplasm where replication takes place. | ||||||||
| 참고사항 | For research use only |
Western blot analysis was performed using anti-P polyclonal antibody at 1ug/mL on various samples.
Lane 1: ATG16620 100ng
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