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| 카탈로그 번호 | HV614014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-PIK3AP1 Polyclonal Antibody (HV614014) is a rabbit polyclonal antibody detecting PIK3AP1 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human PIK3AP1 (Leu489-Ser730). | ||||||||
| 타겟 | BCAP, B-cell phosphoinositide 3-kinase adapter protein 1, PIK3AP1, B-cell adapter for phosphoinositide 3-kinase, Phosphoinositide 3-kinase adapter protein 1 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q6ZUJ8 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Phosphoinositide 3-kinase adapter protein 1 (PIK3AP1) is a ~90 kDa protein. Signaling adapter that contributes to B-cell development by linking B-cell receptor (BCR) signaling to the phosphoinositide 3-kinase (PI3K)-Akt signaling pathway. Has a complementary role to the BCR coreceptor CD19, coupling BCR and PI3K activation by providing a docking site for the PI3K subunit PIK3R1. Alternatively, links Toll-like receptor (TLR) signaling to PI3K activation, a process preventing excessive inflammatory cytokine production. Also involved in the activation of PI3K in natural killer cells. May be involved in the survival of mature B-cells via activation of REL. | ||||||||
| 참고사항 | For research use only. |
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