中文
English
한국어
日本語
Español
Français
Русский
| 카탈로그 번호 | HS844014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-PKN2 Polyclonal Antibody (HS844014) is a rabbit polyclonal antibody detecting PKN2 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat.
Highlights
|
||||||||
| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human PKN2 (Glu67-Ile312). | ||||||||
| 타겟 | PRK2, PKN gamma, PRKCL2, Protein kinase C-like 2, Serine/threonine-protein kinase N2, PKN2, Protein-kinase C-related kinase 2 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q16513 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
||||||||
| 제품 사용 정보 |
| ||||||||
| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Serine/threonine-protein kinase N2 (PKN2) is a ~112 kDa protein. PKC-related serine/threonine-protein kinase and Rho/Rac effector protein that participates in specific signal transduction responses in the cell. Plays a role in the regulation of cell cycle progression, actin cytoskeleton assembly, cell migration, cell adhesion, tumor cell invasion and transcription activation signaling processes. Phosphorylates CTTN in hyaluronan-induced astrocytes and hence decreases CTTN ability to associate with filamentous actin. Phosphorylates HDAC5, therefore lead to impair HDAC5 import. Direct RhoA target required for the regulation of the maturation of primordial junctions into apical junction formation in bronchial epithelial cells. 1. Guen, VJ. et al. (2016) Cell cycle (Georgetown, Tex.) 15, 678-88. PMID: 27104747 | ||||||||
| 참고사항 | For research use only. |
문의하기
+86-027-65523339
중국 우한시 심둔사로 666번지 C동, 우한, 430206
