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| 카탈로그 번호 | HS738014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-PLA1A Polyclonal Antibody (HS738014) is a rabbit polyclonal antibody detecting PLA1A in ELISA, IHC, WB. Suitable for Human and Pongo abelii.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human PLA1A (Leu309-Lys452). | ||||||||
| 타겟 | PSPLA1, PS-PLA1, Phosphatidylserine-specific phospholipase A1, PLA1A, NMD, Phospholipase A1 member A | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q53H76 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Phospholipase A1 member A (PLA1A) is a ~49 kDa protein. Hydrolyzes the ester bond of the acyl group attached at the sn-1 position of phosphatidylserines (phospholipase A1 activity) and 1-acyl-2-lysophosphatidylserines (lysophospholipase activity) in the pathway of phosphatidylserines acyl chain remodeling. Cleaves phosphatidylserines exposed on the outer leaflet of the plasma membrane of apoptotic cells producing 2-acyl-1-lysophosphatidylserines, which in turn enhance mast cell activation and histamine production. Has no activity toward other glycerophospholipids including phosphatidylcholines, phosphatidylethanolamines, phosphatidic acids or phosphatidylinositols, or glycerolipids such as triolein. 1. Nagai, Y. et al. (1999) The Journal of biological chemistry 274, 11053-9. PMID: 10196188 | ||||||||
| 참고사항 | For research use only. |
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