Anti-PLCB3 Polyclonal Antibody (HX907014)

Name: Anti-PLCB3 Polyclonal Antibody
Brand: abinScience
SKU: HX907014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HX907014

설명

Anti-PLCB3 Polyclonal Antibody (HX907014) is a rabbit polyclonal antibody detecting PLCB3 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human PLCB3 (Asp318-Lys468).

타겟

Phospholipase C-beta-3, PLC-beta-3, 1-phosphatidylinositol 4, 5-bisphosphate phosphodiesterase beta-3, Phosphoinositide phospholipase C-beta-3, PLCB3

정제

Purified by antigen affinity column.

등록번호

Q01970

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 (PLCB3) is a ~138 kDa protein. Catalyzes the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Key transducer of G protein-coupled receptor signaling: activated by G(q)/G(11) G alpha proteins downstream of G protein-coupled receptors activation. In neutrophils, participates in a phospholipase C-activating N-formyl peptide-activated GPCR (G protein-coupled receptor) signaling pathway by promoting RASGRP4 activation by DAG, to promote neutrophil functional responses.

1. Waldo, GL. et al. (2010) Science (New York, N.Y.) 330, 974-80. PMID: 20966218

2. Ben-Salem, S. et al. (2018) Journal of medical genetics 55, 122-130. PMID: 29122926

3. Falzone, ME. et al. (2023) Proceedings of the National Academy of Sciences of the United States of America 120, e2315011120. PMID: 37991948

4. Tall, E. et al. (1997) Biochemistry 36, 7239-48. PMID: 9188725

참고사항

For research use only.

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참고 문헌

데이터시트

Anti-PLCB3 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-PLCB3 Polyclonal Antibody (HX907014)

개요

이미지

참고 문헌

데이터시트

SDS