Anti-PPIE Polyclonal Antibody (HV182014)

Name: Anti-PPIE Polyclonal Antibody
Brand: abinScience
SKU: HV182014
Price: 168 USD
Availability: InStock

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개요
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개요

카탈로그 번호

HV182014

설명

Anti-PPIE Polyclonal Antibody (HV182014) is a rabbit polyclonal antibody detecting PPIE in ELISA, IHC, WB. Suitable for Bovine, Human, Mouse, and Pongo abelii.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human PPIE (Tyr41-Val264).

타겟

Peptidyl-prolyl cis-trans isomerase E, PPIE, PPIase E, Cyclophilin-33, CYP33, Rotamase E, Cyclophilin E

정제

Purified by antigen affinity column.

등록번호

Q9UNP9

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Peptidyl-prolyl cis-trans isomerase E (PPIE) is a ~33 kDa protein. Involved in pre-mRNA splicing as component of the spliceosome. Combines RNA-binding and PPIase activities. Binds mRNA and has a preference for single-stranded RNA molecules with poly-A and poly-U stretches, suggesting it binds to the poly(A)-region in the 3'-UTR of mRNA molecules. Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins. Inhibits KMT2A activity; this requires proline isomerase activity.

1. Jurica, MS. et al. (2002) RNA (New York, N.Y.) 8, 426-39. PMID: 11991638

2. Bertram, K. et al. (2017) Nature 542, 318-323. PMID: 28076346

3. Wang, Y. et al. (2008) FEBS letters 582, 835-9. PMID: 18258190

4. Hom, RA. et al. (2010) Journal of molecular biology 400, 145-54. PMID: 20460131

5. Park, S. et al. (2010) Biochemistry 49, 6576-86. PMID: 20677832

6. Mi, H. et al. (1996) FEBS letters 398, 201-5. PMID: 8977107

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-PPIE Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-PPIE Polyclonal Antibody (HV182014)

개요

이미지

참고 문헌

데이터시트

SDS