

| 카탈로그 번호 | HW659014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-PPM1A Polyclonal Antibody (HW659014) is a rabbit polyclonal antibody detecting PPM1A in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Bovine.
Highlights
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| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human PPM1A (Gly2-Trp382). | ||||||||
| 타겟 | Protein phosphatase 2C isoform alpha, PPPM1A, Protein phosphatase 1A, Protein phosphatase IA, PP2C-alpha, PPM1A | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P35813 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Protein phosphatase 1A (PPM1A) is a ~42 kDa protein. Enzyme with a broad specificity. Negatively regulates TGF-beta signaling through dephosphorylating SMAD2 and SMAD3, resulting in their dissociation from SMAD4, nuclear export of the SMADs and termination of the TGF-beta-mediated signaling. Dephosphorylates PRKAA1 and PRKAA2. Plays an important role in the termination of TNF-mediated NF-kappa-B activation through dephosphorylating and inactivating IKBKB/IKKB. | ||||||||
| 참고사항 | For research use only. |
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