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| 카탈로그 번호 | JN126014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-pptT Polyclonal Antibody (JN126014) is a rabbit polyclonal antibody detecting 4'-phosphopantetheinyl transferase PptT; PPTase; 2.7.8.7; pptT; Rv2794c in ELISA, IHC, WB.
Highlights
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| 종 반응성 | Mycobacterium tuberculosis | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant pptT (Met1-Leu227). | ||||||||
| 타겟 | 4'-phosphopantetheinyl transferase PptT; PPTase; 2.7.8.7; pptT; Rv2794c | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | O33336 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | 4'-phosphopantetheinyl transferase PptT is a ~24 kDa protein. Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. Involved in post-translational modification of various type-I polyketide synthases required for the formation of both mycolic acids and lipid virulence factors. Acts on Pks13, Mas, PpsA, PpsB, PpsC and PpsD. Also acts on AcpM, the meromycolate extension acyl carrier protein. In addition, is involved in the activation of the acyl carrier protein MbtL and the nonribosomal peptides synthases MbtB and MbtE, which are involved in the biosynthesis of the siderophore mycobactin. 1. Chalut, C. et al. (2006) Proceedings of the National Academy of Sciences of the United States of America 103, 8511-6. PMID: 16709676 2. Zimhony, O. et al. (2015) Biochemistry 54, 2360-71. PMID: 25785780 3. Jung, J. et al. (2016) FEBS open bio 6, 1220-1226. PMID: 28203522 4. Quadri, LE. et al. (1998) Chemistry & biology 5, 631-45. PMID: 9831524 | ||||||||
| 참고사항 | For research use only |
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