Anti-PQBP1 Polyclonal Antibody (HF653014)

Name: Anti-PQBP1 Polyclonal Antibody
Brand: abinScience
SKU: HF653014
Price: 168 USD
Availability: InStock

데이터시트 제품 공유 정보 복사

가격(USD): --

사양:

50ug
100ug

수량:

문의하기

개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호

HF653014

설명

Anti-PQBP1 Polyclonal Antibody (HF653014) is a rabbit polyclonal antibody detecting PQBP1 in ELISA, IHC, WB. Suitable for Bovine, Human, Mouse, Pongo pygmaeus, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human PQBP1 (Met1-Asp265).

타겟

NPW38, PQBP1, Polyglutamine tract-binding protein 1, PQBP-1, Npw38, 38 kDa nuclear protein containing a WW domain, Polyglutamine-binding protein 1

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

O60828

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Polyglutamine-binding protein 1 (PQBP1) is a ~30 kDa protein. Intrinsically disordered protein that acts as a scaffold, and which is involved in different processes, such as pre-mRNA splicing, transcription regulation, innate immunity and neuron development. Interacts with splicing-related factors via the intrinsically disordered region and regulates alternative splicing of target pre-mRNA species. May suppress the ability of POU3F2 to transactivate the DRD1 gene in a POU3F2 dependent manner. Can activate transcription directly or via association with the transcription machinery. May be involved in ATXN1 mutant-induced cell death.

1. Komuro, A. et al. (1999) Nucleic acids research 27, 1957-65. PMID: 10198427

2. Waragai, M. et al. (1999) Human molecular genetics 8, 977-87. PMID: 10332029

3. Okazawa, H. et al. (2002) Neuron 34, 701-13. PMID: 12062018

4. Tapia, VE. et al. (2010) The Journal of biological chemistry 285, 19391-401. PMID: 20410308

5. Wang, Q. et al. (2013) Genes & development 27, 615-26. PMID: 23512658

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-PQBP1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-PQBP1 Polyclonal Antibody (HF653014)

개요

이미지

참고 문헌

데이터시트

SDS