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| 카탈로그 번호 | VK500114 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Protease 3C Polyclonal Antibody (VK500114) is a rabbit polyclonal antibody detecting Protease 3C in ELISA, IHC, WB.
Highlights
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| 종 반응성 | Foot-and-mouth disease virus (FMDV) | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Genome polyprotein (Ser1650-Glu1862). | ||||||||
| 타겟 | Genome polyprotein, Leader protease, Lpro, EC:3.4.22.46, Capsid protein VP0, VP4-VP2, Capsid protein VP4, P1A, Virion protein 4, Capsid protein VP2, P1B, Virion protein 2, Capsid protein VP3, P1C, Virion protein 3, Capsid protein VP1, P1D, Virion protein 1, Protein 2A, P2A, P52, Protein 2B, P2B, Protein 2C, P2C, EC:3.6.1.15, Protein 3A, P3A, Protein 3B-1, P3B-1, Genome-linked protein VPg1, Protein 3B-2, P3B-2, Genome-linked protein VPg2, Protein 3B-3, P3B-3, Genome-linked protein VPg3, Protease 3C, EC:3.4.22.28, Picornain 3C, P3C, Protease P20B, RNA-directed RNA polymerase 3D-POL, P3D-POL, EC:2.7.7.48, P56A | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P03307 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Genome polyprotein is a ~259 kDa protein. Autocatalytically cleaves itself from the polyprotein at the L/VP0 junction. Also cleaves the host translation initiation factors EIF4G1 and EIF4G3, in order to shut off the capped cellular mRNA transcription. Plays a role in counteracting host innate antiviral response using diverse mechanisms. Possesses a deubiquitinase activity acting on both 'Lys-48' and 'Lys-63'-linked polyubiquitin chains. In turn, inhibits the ubiquitination and subsequent activation of key signaling molecules of type I IFN response such as host RIGI, TBK1, TRAF3 and TRAF6. | ||||||||
| 참고사항 | For research use only |
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