Anti-PTBP1 Polyclonal Antibody (HB835014)

Name: Anti-PTBP1 Polyclonal Antibody
Brand: abinScience
SKU: HB835014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HB835014

설명

Anti-PTBP1 Polyclonal Antibody (HB835014) is a rabbit polyclonal antibody detecting PTBP1 in ELISA, IHC, WB. Suitable for Human, Mouse, Bovine, Rat, and Pig.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human PTBP1 (Met1-Ile531).

타겟

PTB, Polypyrimidine tract-binding protein 1, 57 kDa RNA-binding protein PPTB-1, PTBP1, Heterogeneous nuclear ribonucleoprotein I, hnRNP I

정제

Purified by antigen affinity column.

등록번호

P26599

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Polypyrimidine tract-binding protein 1 (PTBP1) is a ~59 kDa protein. Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA.

1. Wang, J. et al. (2004) Journal of neurochemistry 88, 1078-90. PMID: 15009664

2. Zuccato, E. et al. (2004) The Journal of biological chemistry 279, 16980-8. PMID: 14966131

3. David, CJ. et al. (2010) Nature 463, 364-8. PMID: 20010808

4. Kafasla, P. et al. (2011) RNA (New York, N.Y.) 17, 1120-31. PMID: 21518806

참고사항

For research use only.

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참고 문헌

데이터시트

Anti-PTBP1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-PTBP1 Polyclonal Antibody (HB835014)

개요

이미지

참고 문헌

데이터시트

SDS