

| 카탈로그 번호 | HB946014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-PTPN1 Polyclonal Antibody (HB946014) is a rabbit polyclonal antibody detecting PTPN1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Chicken.
Highlights
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| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human PTPN1 (Met1-Asn321). | ||||||||
| 타겟 | PTPN1, PTP-1B, Tyrosine-protein phosphatase non-receptor type 1, Protein-tyrosine phosphatase 1B, PTP1B | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P18031 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Tyrosine-protein phosphatase non-receptor type 1 (PTPN1) is a ~49 kDa protein. Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-src-induced signal transduction cascades. May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion. May also regulate the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET. | ||||||||
| 참고사항 | For research use only. |

Lane 1: Hela cell lysate
Lane 2: MCF-7 cell lysate
Lane 3: A549 cell lysate


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