Anti-PTPN4 Polyclonal Antibody (HA691014)

Name: Anti-PTPN4 Polyclonal Antibody
Brand: abinScience
SKU: HA691014
Price: 96 USD
Availability: InStock

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개요
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SDS

개요

카탈로그 번호

HA691014

설명

Anti-PTPN4 Polyclonal Antibody (HA691014) is a rabbit polyclonal antibody detecting Tyrosine-protein phosphatase non-receptor type 4; 3.1.3.48; Protein-tyrosine phosphatase MEG1; MEG; PTPase-MEG1; PTPN4 in ELISA, IHC, WB. Suitable for Human and Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human, Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant human PTPN4 (Asp636-Lys926).

타겟

Tyrosine-protein phosphatase non-receptor type 4; 3.1.3.48; Protein-tyrosine phosphatase MEG1; MEG; PTPase-MEG1; PTPN4

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

P29074, Q9WU22

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Tyrosine-protein phosphatase non-receptor type 4 (PTPN4) is a ~105 kDa protein. Phosphatase that plays a role in immunity, learning, synaptic plasticity or cell homeostasis. Regulates neuronal cell homeostasis by protecting neurons against apoptosis. Negatively regulates TLR4-induced interferon beta production by dephosphorylating adapter TICAM2 and inhibiting subsequent TRAM-TRIF interaction. Also dephosphorylates the immunoreceptor tyrosine-based activation motifs/ITAMs of the TCR zeta subunit and thereby negatively regulates TCR-mediated signaling pathway. May act at junctions between the membrane and the cytoskeleton.

1. Huai, W. et al. (2015) Journal of immunology (Baltimore, Md. : 1950) 194, 4458-65. PMID: 25825441

2. Maisonneuve, P. et al. (2016) The Journal of biological chemistry 291, 16699-708. PMID: 27246854

3. Préhaud, C. et al. (2010) Science signaling 3, ra5. PMID: 20086240

참고사항

For research use only

이미지

참고 문헌

데이터시트

Anti-PTPN4 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-PTPN4 Polyclonal Antibody (HA691014)

개요

이미지

참고 문헌

데이터시트

SDS