

| 카탈로그 번호 | HS786014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-QPCT Polyclonal Antibody (HS786014) is a rabbit polyclonal antibody detecting QPCT in ELISA, IHC, WB. Suitable for Bovine and Human.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human QPCT (Val29-Leu361). | ||||||||
| 타겟 | sQC, Glutaminyl-tRNA cyclotransferase, QC, QPCT, Glutamyl cyclase, EC, Glutaminyl-peptide cyclotransferase, Glutaminyl cyclase | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q16769 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Glutaminyl-peptide cyclotransferase (QPCT) is a ~40 kDa protein. Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue. Also catalyzes N-terminal pyroglutamate formation. In vitro, catalyzes pyroglutamate formation of N-terminally truncated form of APP amyloid-beta peptides [Glu-3]-amyloid-beta. May be involved in the N-terminal pyroglutamate formation of several amyloid-related plaque-forming peptides. | ||||||||
| 참고사항 | For research use only. |
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