Anti-RAD21 Polyclonal Antibody (HA549014)

Name: Anti-RAD21 Polyclonal Antibody
Brand: abinScience
SKU: HA549014
Price: 96 USD
Availability: InStock

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개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호

HA549014

설명

Anti-RAD21 Polyclonal Antibody (HA549014) is a rabbit polyclonal antibody detecting RAD21 in WB, IHC, ELISA. Suitable for Human, Mus musculus, and Bovine.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse

응용 분야

WB, IHC, ELISA

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant RAD21 (Glu147-Thr349).

타겟

RAD21

내독소 수준

Please contact with the lab for this information.

순도

>90% as determined by SDS-PAGE.

정제

Purified by antigen affinity column.

등록번호

O60216

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

대체 이름

Double-strand-break repair protein rad21 homolog, hHR21, Nuclear matrix protein 1, NXP-1, SCC1 homolog, 64-kDa C-terminal product, 64-kDa carboxy-terminal product, 65-kDa carboxy-terminal product, RAD21

배경

Double-strand-break repair protein rad21 homolog is a ~71 kDa protein. As a member of the cohesin complex, involved in sister chromatid cohesion from the time of DNA replication in S phase to their segregation in mitosis, a function that is essential for proper chromosome segregation, post-replicative DNA repair, and the prevention of inappropriate recombination between repetitive regions. The cohesin complex may also play a role in spindle pole assembly during mitosis. In interphase, cohesins may function in the control of gene expression by binding to numerous sites within the genome. May control RUNX1 gene expression (Probable). Binds to and represses APOB gene promoter.

1. Hauf, S. et al. (2001) Science (New York, N.Y.) 293, 1320-3. PMID: 11509732

2. Gregson, HC. et al. (2001) The Journal of biological chemistry 276, 47575-82. PMID: 11590136

3. Bonora, E. et al. (2015) Gastroenterology 148, 771-782.e11. PMID: 25575569

참고사항

For research use only.

이미지

Western blot

Western blot analysis was performed using anti-RAD21 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Hela cell lysate
Lane 2: K562 cell lysate

참고 문헌

데이터시트

Anti-RAD21 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-RAD21 Polyclonal Antibody (HA549014)

개요

이미지

참고 문헌

데이터시트

SDS