Anti-RALA Polyclonal Antibody (HY266014)

Name: Anti-RALA Polyclonal Antibody
Brand: abinScience
SKU: HY266014
Price: 168 USD
Availability: InStock

데이터시트 제품 공유 정보 복사

가격(USD): --

사양:

50ug
100ug

수량:

문의하기

개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호

HY266014

설명

Anti-RALA Polyclonal Antibody (HY266014) is a rabbit polyclonal antibody detecting RALA in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, and Saguinus oedipus.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human RALA (Met1-Leu206).

타겟

Ras-related protein Ral-A, RAL, RALA

정제

Purified by antigen affinity column.

등록번호

P11233

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Ras-related protein Ral-A (RALA) is a ~23 kDa protein. Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. The RALA-exocyst complex regulates integrin-dependent membrane raft exocytosis and growth signaling. Key regulator of LPAR1 signaling and competes with GRK2 for binding to LPAR1 thus affecting the signaling properties of the receptor.

1. Cascone, I. et al. (2008) The EMBO journal 27, 2375-87. PMID: 18756269

2. Aziziyeh, AI. et al. (2009) Cellular signalling 21, 1207-17. PMID: 19306925

3. Balasubramanian, N. et al. (2010) Current biology : CB 20, 75-9. PMID: 20005108

4. Kashatus, DF. et al. (2011) Nature cell biology 13, 1108-15. PMID: 21822277

5. Hiatt, SM. et al. (2018) PLoS genetics 14, e1007671. PMID: 30500825

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-RALA Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-RALA Polyclonal Antibody (HY266014)

개요

이미지

참고 문헌

데이터시트

SDS