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| 카탈로그 번호 | HW462014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-RCVRN Polyclonal Antibody (HW462014) is a rabbit polyclonal antibody detecting RCVRN in ELISA, IHC, WB. Suitable for Human, Mouse, Dog, and Bovine.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human RCVRN (Gly2-Ala200). | ||||||||
| 타겟 | RCVRN, Recoverin, RCV1, Cancer-associated retinopathy protein, Protein CAR | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P35243 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Recoverin (RCVRN) is a ~23 kDa protein. Acts as a calcium sensor and regulates phototransduction of cone and rod photoreceptor cells. Modulates light sensitivity of cone photoreceptor in dark and dim conditions. In response to high Ca(2+) levels induced by low light levels, prolongs RHO/rhodopsin activation in rod photoreceptor cells by binding to and inhibiting GRK1-mediated phosphorylation of RHO/rhodopsin. Plays a role in scotopic vision/enhances vision in dim light by enhancing signal transfer between rod photoreceptors and rod bipolar cells. Improves rod photoreceptor sensitivity in dim light and mediates response of rod photoreceptors to facilitate detection of change and motion in bright light. | ||||||||
| 참고사항 | For research use only. |
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