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Anti-RNASE7 Polyclonal Antibody (HV262014)

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개요
카탈로그 번호HV262014
설명
Anti-RNASE7 Polyclonal Antibody (HV262014) is a rabbit polyclonal antibody detecting RNASE7 in ELISA, IHC, WB. Suitable for Human.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
종 반응성Human
응용 분야ELISA, IHC, WB
숙주 종Rabbit
클론성Polyclonal
이소타입IgG
면역원 E. coli - derived recombinant Human RNASE7 (Lys31-Val155).
타겟 Skin-derived antimicrobial protein 2, RNASE7, Ribonuclease 7, RNase 7, SAP-2
정제 Purified by antigen affinity column.
등록번호 Q9H1E1
형태 Liquid
저장 완충액 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보
응용 분야 희석
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
안정성 및 저장 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
배경

Ribonuclease 7 (RNASE7) is a ~17 kDa protein. Exhibits a potent RNase activity. Has broad-spectrum antimicrobial activity against many pathogenic microorganisms including uropathogenic E.coli (UPEC), and remarkably potent activity (lethal dose of 90% < 30 nM) against a vancomycin resistant Enterococcus faecium. Causes loss of bacterial membrane integrity. Probably contributes to urinary tract sterility. Bactericidal activity is independent of RNase activity.

1. Harder, J. et al. (2002) The Journal of biological chemistry 277, 46779-84. PMID: 12244054
2. Zhang, J. et al. (2003) Nucleic acids research 31, 602-7. PMID: 12527768
3. Huang, YC. et al. (2007) The Journal of biological chemistry 282, 4626-4633. PMID: 17150966
4. Becknell, B. et al. (2015) Kidney international 87, 151-61. PMID: 25075772
5. Bender, K. et al. (2021) American journal of physiology. Renal physiology 320, F972-F983. PMID: 33818125
참고사항 For research use only.
이미지
참고 문헌
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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