

| 카탈로그 번호 | HV262014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-RNASE7 Polyclonal Antibody (HV262014) is a rabbit polyclonal antibody detecting RNASE7 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human RNASE7 (Lys31-Val155). | ||||||||
| 타겟 | Skin-derived antimicrobial protein 2, RNASE7, Ribonuclease 7, RNase 7, SAP-2 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q9H1E1 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Ribonuclease 7 (RNASE7) is a ~17 kDa protein. Exhibits a potent RNase activity. Has broad-spectrum antimicrobial activity against many pathogenic microorganisms including uropathogenic E.coli (UPEC), and remarkably potent activity (lethal dose of 90% < 30 nM) against a vancomycin resistant Enterococcus faecium. Causes loss of bacterial membrane integrity. Probably contributes to urinary tract sterility. Bactericidal activity is independent of RNase activity. 1. Harder, J. et al. (2002) The Journal of biological chemistry 277, 46779-84. PMID: 12244054 2. Zhang, J. et al. (2003) Nucleic acids research 31, 602-7. PMID: 12527768 3. Huang, YC. et al. (2007) The Journal of biological chemistry 282, 4626-4633. PMID: 17150966 4. Becknell, B. et al. (2015) Kidney international 87, 151-61. PMID: 25075772 5. Bender, K. et al. (2021) American journal of physiology. Renal physiology 320, F972-F983. PMID: 33818125 | ||||||||
| 참고사항 | For research use only. |
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