Anti-RNF113A Polyclonal Antibody (HB570014)

Name: Anti-RNF113A Polyclonal Antibody
Brand: abinScience
SKU: HB570014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HB570014

설명

Anti-RNF113A Polyclonal Antibody (HB570014) is a rabbit polyclonal antibody detecting E3 ubiquitin-protein ligase RNF113A; 2.3.2.27; Cwc24 homolog; RING finger protein 113A; Zinc finger protein 183; RNF113A; RNF113; ZNF183 in ELISA, IHC, WB. Suitable for Human and Bovine.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant human RNF113A (Ile201-Thr343).

타겟

E3 ubiquitin-protein ligase RNF113A; 2.3.2.27; Cwc24 homolog; RING finger protein 113A; Zinc finger protein 183; RNF113A; RNF113; ZNF183

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

O15541, Q67ER4

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

E3 ubiquitin-protein ligase RNF113A is a ~38 kDa protein. Required for pre-mRNA splicing as component of the spliceosome. As a component of the minor spliceosome, involved in the splicing of U12-type introns in pre-mRNAs (Probable). E3 ubiquitin-protein ligase that catalyzes the transfer of ubiquitin onto target proteins. Catalyzes polyubiquitination of SNRNP200/BRR2 with non-canonical 'Lys-63'-linked polyubiquitin chains. Plays a role in DNA repair via its role in the synthesis of 'Lys-63'-linked polyubiquitin chains that recruit ALKBH3 and the ASCC complex to sites of DNA damage by alkylating agents.

1. Zhang, X. et al. (2018) Cell research 28, 307-322. PMID: 29360106

2. Haselbach, D. et al. (2018) Cell 172, 454-464.e11. PMID: 29361316

3. Lear, T. et al. (2017) American journal of physiology. Cell physiology 313, C584-C592. PMID: 28978524

4. Brickner, JR. et al. (2017) Nature 551, 389-393. PMID: 29144457

참고사항

For research use only

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참고 문헌

데이터시트

Anti-RNF113A Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-RNF113A Polyclonal Antibody (HB570014)

개요

이미지

참고 문헌

데이터시트

SDS