

| 카탈로그 번호 | HB475014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-RNF19B Polyclonal Antibody (HB475014) is a rabbit polyclonal antibody detecting E3 ubiquitin-protein ligase RNF19B; 2.3.2.31; IBR domain-containing protein 3; Natural killer lytic-associated molecule; RING finger protein 19B; RNF19B; IBRDC3; NKLAM in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
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| 종 반응성 | Human, Mouse | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant human RNF19B (Ala114-Ser323). | ||||||||
| 타겟 | E3 ubiquitin-protein ligase RNF19B; 2.3.2.31; IBR domain-containing protein 3; Natural killer lytic-associated molecule; RING finger protein 19B; RNF19B; IBRDC3; NKLAM | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q6ZMZ0, A2A7Q9 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | E3 ubiquitin-protein ligase RNF19B is a ~77 kDa protein. E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates, such as UCKL1. Involved in the cytolytic activity of natural killer cells and cytotoxic T-cells. Protects against staurosporin-induced cell death. 1. Fortier, JM. et al. (2006) Journal of immunology (Baltimore, Md. : 1950) 176, 6454-63. PMID: 16709802 2. Kaneko, M. et al. (2016) Scientific reports 6, 30955. PMID: 27485036 3. Kozlowski, M. et al. (1999) Journal of immunology (Baltimore, Md. : 1950) 163, 1775-85. PMID: 10438909 | ||||||||
| 참고사항 | For research use only |
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