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| 카탈로그 번호 | HP096013 | ||||||
|---|---|---|---|---|---|---|---|
| 설명 |
Anti-RTN4R/NgR1/Nogor Recombinant Antibody (M5) (HP096013) is a human monoclonal antibody detecting RTN4R/NgR1/Nogor in ELISA, FCM, IF, IP, SPR, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human | ||||||
| 응용 분야 | ELISA, FCM, IF, IP, SPR, WB | ||||||
| 숙주 종 | Human | ||||||
| 클론성 | Monoclonal | ||||||
| 이소타입 | IgG1, kappa | ||||||
| 클론 ID | M5 | ||||||
| 타겟 | NgR, Nogo receptor, Reticulon-4 receptor, RTN4R, Nogo-66 receptor, NOGOR | ||||||
| 내독소 수준 | < 10 EU/mg as determined by LAL method. | ||||||
| 순도 | >95% as determined by SDS-PAGE. | ||||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||||
| 등록번호 | Q9BZR6 | ||||||
| RRID | Anti-RTN4R/NgR1/Nogor Antibody (M5) (abinScience Cat# HP096013, RRID:AB_3729079) |
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| 형태 | Liquid | ||||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||||
| 배경 | Reticulon-4 receptor (RTN4R/NgR1) is a ~50 kDa protein. Receptor for RTN4, OMG and MAG. Functions as a receptor for the sialylated gangliosides GT1b and GM1. Besides, functions as a receptor for chondroitin sulfate proteoglycans. Can also bind heparin. Intracellular signaling cascades are triggered via the coreceptor NGFR. 1. GrandPré, T. et al. (2002) Nature 417, 547-51. PMID: 12037567 2. Wang, KC. et al. (2002) Nature 417, 941-4. PMID: 12068310 3. Liu, BP. et al. (2002) Science (New York, N.Y.) 297, 1190-3. PMID: 12089450 4. Wong, ST. et al. (2002) Nature neuroscience 5, 1302-8. PMID: 12426574 5. Barton, WA. et al. (2003) The EMBO journal 22, 3291-302. PMID: 12839991 6. Teusch, N. et al. (2006) Assay and drug development technologies 4, 133-41. PMID: 16712417 7. Williams, G. et al. (2008) The Journal of biological chemistry 283, 16641-52. PMID: 18411262 8. Budel, S. et al. (2008) The Journal of neuroscience : the official journal of the Society for Neuroscience 28, 13161-72. PMID: 19052207 9. Wills, ZP. et al. (2012) Neuron 73, 466-81. PMID: 22325200 | ||||||
| 참고사항 | For research use only. | ||||||
| Isotype Control | Human IgG1 (LALAPG) Recombinant Isotype Control Antibody (HyHEL-10) (HP688307) Human IgG1 (LALA) Recombinant Isotype Control Antibody (HyHEL-10) (HP688107) |
SDS-PAGE for Anti-RTN4R/NgR1/Nogor Antibody (M5)
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