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| 카탈로그 번호 | HV465014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human SCARA5 (Gln118-His495). | ||||||||
| 타겟 | SCARA5, Scavenger receptor hlg, Scavenger receptor class A member 5 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q6ZMJ2 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Scavenger receptor class A member 5 (SCARA5) is a ~53 kDa protein. Ferritin receptor that mediates non-transferrin-dependent delivery of iron. Mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. Preferentially binds ferritin light chain (FTL) compared to heavy chain (FTH1). | ||||||||
| 참고사항 | For research use only. |
Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with SCARA5 antibody (HV465014) at 1 μg/ml.
Lane 1: Recombinant protein
Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (TF690314) at 0.1 μg/mL.
Predict MW: 43 kDa
Observed MW: 43 kDa
Rat Muscle lysates were subjected to SDS PAGE followed by western blot with SCARA5 antibody (HV465014) at 1 μg/ml.
Lane 1: Rat Muscle lysates
Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (TF690314) at 0.1 μg/mL.
Predict MW: 43 kDa
Observed MW: 43 kDa
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