

| 카탈로그 번호 | HV327014 | ||||||||
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| 설명 |
Anti-SIAE Polyclonal Antibody (HV327014) is a rabbit polyclonal antibody detecting SIAE in ELISA, IHC, WB. Suitable for Human and Pongo abelii.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human SIAE (Ala22-Pro244). | ||||||||
| 타겟 | YSG2, H-Lse, Sialic acid-specific 9-O-acetylesterase, Sialate O-acetylesterase, SIAE | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q9HAT2 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Sialate O-acetylesterase (SIAE) is a ~58 kDa protein. Catalyzes the removal of O-acetyl ester groups from position 9 of the free diacetylated sialate N-acetyl-9-O-acetylneuraminate (Neu5,9Ac2) in the cytosol and of the diacetylated sialate residues of sialylglycoconjugates in the lysosomes (Probable). Together with the sialate-O-acetyltransferase they regulate the balance of acetylated sialoglycoconjugates, key players in various processes such as cell-cell interactions, host-pathogen recognition, and tumor antigenicity. 1. Mandal, C. et al. (2012) Glycobiology 22, 70-83. PMID: 21803834 | ||||||||
| 참고사항 | For research use only. |
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