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| 카탈로그 번호 | VK100034 | ||||
|---|---|---|---|---|---|
| 설명 |
Anti-SIV VIF Polyclonal Antibody (VK100034) is a rabbit polyclonal antibody detecting vif protein in ELISA, IHC, WB.
Highlights
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| 종 반응성 | Simian immunodeficiency virus (SIV) | ||||
| 응용 분야 | ELISA, IHC, WB | ||||
| 숙주 종 | Rabbit | ||||
| 클론성 | Polyclonal | ||||
| 이소타입 | IgG | ||||
| 면역원 | E. coli - derived recombinant SIV VIF (Met1-Ser176). | ||||
| 타겟 | vif protein, vif | ||||
| 내독소 수준 | Please contact with the lab for this information. | ||||
| 정제 | Purified by antigen affinity column. | ||||
| 등록번호 | Q02841 | ||||
| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| 배경 | Virion infectivity factor (VIF) is a ~26 kDa protein. Counteracts the innate antiviral activity of APOBEC3G. Forms a complex with host APOBEC3G thus preventing the entry of this lethally hypermutating enzyme into progeny virions. Functions as an adapter molecule, recruiting APOBEC3G to the ubiquitin-proteasome machinery. Targets APOBEC3G for degradation through the assembly with elongin BC complex, CUL5 and RBX1. Binds viral RNA and affects the stability of viral nucleoprotein core. | ||||
| 참고사항 | For research use only. |
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