Anti-SKP1 Polyclonal Antibody (HX846014)

Name: Anti-SKP1 Polyclonal Antibody
Brand: abinScience
SKU: HX846014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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개요

카탈로그 번호

HX846014

설명

Anti-SKP1 Polyclonal Antibody (HX846014) is a rabbit polyclonal antibody detecting SKP1 in ELISA, IHC, WB. Suitable for Bovine, Cavia porcellus, Chicken, Human, and Macaca fascicularis.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human SKP1 (Met1-Lys163).

타겟

p19A, Organ of Corti protein 2, EMC19, SKP1, Organ of Corti protein II, OCP2, OCP-2, RNA polymerase II elongation factor-like protein, Cyclin-A/CDK2-associated protein p19, OCP-II, p19skp1, TCEB1L, S-phase kinase-associated protein 1, SIII, Transcription elongation factor B polypeptide 1-like, SKP1A

정제

Purified by antigen affinity column.

등록번호

P63208

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

S-phase kinase-associated protein 1 (SKP1) is a ~18 kDa protein. Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. The functional specificity of the SCF complex depends on the F-box protein as substrate recognition component. SCF(BTRC) and SCF(FBXW11) direct ubiquitination of CTNNB1 and participate in Wnt signaling. SCF(FBXW11) directs ubiquitination of phosphorylated NFKBIA.

1. Man, X. et al. (2015) European journal of cell biology 94, 162-72. PMID: 25704143

2. Hopf, LVM. et al. (2022) Nature structural & molecular biology 29, 854-862. PMID: 35982156

3. Cao, Y. et al. (2023) The EMBO journal 42, e113033. PMID: 36896912

참고사항

For research use only.

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참고 문헌

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Anti-SKP1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-SKP1 Polyclonal Antibody (HX846014)

개요

이미지

참고 문헌

데이터시트

SDS

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