

| 카탈로그 번호 | HA797014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-SLBP Polyclonal Antibody (HA797014) is a rabbit polyclonal antibody detecting Histone RNA hairpin-binding protein; Histone stem-loop-binding protein; SLBP; HBP in ELISA, IHC, WB. Suitable for Human and Mouse.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant human SLBP (Cys72-Asp198). | ||||||||
| 타겟 | Histone RNA hairpin-binding protein; Histone stem-loop-binding protein; SLBP; HBP | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q14493, P97440 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Histone RNA hairpin-binding protein (SLBP) is a ~31 kDa protein. RNA-binding protein involved in the histone pre-mRNA processing. Binds the stem-loop structure of replication-dependent histone pre-mRNAs and contributes to efficient 3'-end processing by stabilizing the complex between histone pre-mRNA and U7 small nuclear ribonucleoprotein (snRNP), via the histone downstream element (HDE). Plays an important role in targeting mature histone mRNA from the nucleus to the cytoplasm and to the translation machinery. Stabilizes mature histone mRNA and could be involved in cell-cycle regulation of histone gene expression. Involved in the mechanism by which growing oocytes accumulate histone proteins that support early embryogenesis. 1. Zheng, L. et al. (2003) Molecular and cellular biology 23, 1590-601. PMID: 12588979 2. Sullivan, KD. et al. (2009) RNA (New York, N.Y.) 15, 459-72. PMID: 19155325 3. Wang, ZF. et al. (1996) Genes & development 10, 3028-40. PMID: 8957003 4. Martin, F. et al. (1997) The EMBO journal 16, 769-78. PMID: 9049306 | ||||||||
| 참고사항 | For research use only |
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