Anti-SORD Polyclonal Antibody (HX841014)

Name: Anti-SORD Polyclonal Antibody
Brand: abinScience
SKU: HX841014
Price: 168 USD
Availability: InStock

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100ug

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개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호

HX841014

설명

Anti-SORD Polyclonal Antibody (HX841014) is a rabbit polyclonal antibody detecting SORD in ELISA, IHC, WB. Suitable for Human, Bovine, Macaca fascicularis, Ovis aries, and Pongo abelii.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human SORD (Ala98-Gln355).

타겟

(R, R)-butanediol dehydrogenase, RDH, Polyol dehydrogenase, Sorbitol dehydrogenase, Ribitol dehydrogenase, SORD, Xylitol dehydrogenase, XDH, L-iditol 2-dehydrogenase, SDH

정제

Purified by antigen affinity column.

등록번호

Q00796

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Sorbitol dehydrogenase (SORD) is a ~38 kDa protein. Polyol dehydrogenase that catalyzes the reversible NAD(+)-dependent oxidation of various sugar alcohols. Is mostly active with D-sorbitol (D-glucitol), L-threitol, xylitol and ribitol as substrates, leading to the C2-oxidized products D-fructose, L-erythrulose, D-xylulose, and D-ribulose, respectively. Is a key enzyme in the polyol pathway that interconverts glucose and fructose via sorbitol, which constitutes an important alternate route for glucose metabolism. The polyol pathway is believed to be involved in the etiology of diabetic complications, such as diabetic neuropathy and retinopathy, induced by hyperglycemia. May play a role in sperm motility by using sorbitol as an alternative energy source for sperm motility.

1. Maret, W. et al. (1988) Biochemistry 27, 1622-8. PMID: 3365415

2. Pauly, TA. et al. (2003) Structure (London, England : 1993) 11, 1071-85. PMID: 12962626

3. Safi, SZ. et al. (2014) BioMed research international 2014, 801269. PMID: 25105142

4. Dewanjee, S. et al. (2018) European journal of pharmacology 833, 472-523. PMID: 29966615

5. Frenette, G. et al. (2006) Journal of andrology 27, 233-9. PMID: 16278369

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-SORD Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-SORD Polyclonal Antibody (HX841014)

개요

이미지

참고 문헌

데이터시트

SDS