

| 카탈로그 번호 | HW480014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-SOX9 Polyclonal Antibody (HW480014) is a rabbit polyclonal antibody detecting SOX9 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Callithrix jacchus, and Dog.
Highlights
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| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human SOX9 (Met1-Lys151). | ||||||||
| 타겟 | Transcription factor SOX-9, SOX9 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P48436 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Transcription factor SOX-9 (SOX9) is a ~56 kDa protein. Transcription factor that plays a key role in chondrocytes differentiation and skeletal development. Specifically binds the 5'-ACAAAG-3' DNA motif present in enhancers and super-enhancers and promotes expression of genes important for chondrogenesis, including cartilage matrix protein-coding genes COL2A1, COL4A2, COL9A1, COL11A2 and ACAN, SOX5 and SOX6. Also binds to some promoter regions. Plays a central role in successive steps of chondrocyte differentiation. Absolutely required for precartilaginous condensation, the first step in chondrogenesis during which skeletal progenitors differentiate into prechondrocytes. 1. Matsushita, M. et al. (2013) American journal of medical genetics. Part A 161A, 2528-34. PMID: 24038782 2. Südbeck, P. et al. (1996) Nature genetics 13, 230-2. PMID: 8640233 | ||||||||
| 참고사항 | For research use only. |
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