Anti-SRC Polyclonal Antibody (HY387014)

Name: Anti-SRC Polyclonal Antibody
Brand: abinScience
SKU: HY387014
Price: 168 USD
Availability: InStock

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개요
이미지
참고 문헌
데이터시트
SDS

개요

카탈로그 번호

HY387014

설명

Anti-SRC Polyclonal Antibody (HY387014) is a rabbit polyclonal antibody detecting SRC in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Avian sarcoma virus, and Danio rerio.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human SRC (Tyr187-Leu536).

타겟

SRC1, p60-Src, Proto-oncogene tyrosine-protein kinase Src, Proto-oncogene c-Src, SRC, pp60c-src

정제

Purified by antigen affinity column.

등록번호

P12931

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Proto-oncogene tyrosine-protein kinase Src is a ~59 kDa protein. Non-receptor protein tyrosine kinase which is activated following engagement of many different classes of cellular receptors including immune response receptors, integrins and other adhesion receptors, receptor protein tyrosine kinases, G protein-coupled receptors as well as cytokine receptors. Participates in signaling pathways that control a diverse spectrum of biological activities including gene transcription, immune response, cell adhesion, cell cycle progression, apoptosis, migration, and transformation. Due to functional redundancy between members of the SRC kinase family, identification of the specific role of each SRC kinase is very difficult. SRC appears to be one of the primary kinases activated following engagement of receptors and plays a role in the activation of other protein tyrosine kinase (PTK) families. Receptor clustering or dimerization leads to recruitment of SRC to the receptor complexes where it phosphorylates the tyrosine residues within the receptor cytoplasmic domains.

1. Paré, G. et al. (2021) Frontiers in immunology 12, 650808. PMID: 34234773

2. Wang, Y. et al. (2011) Molecular biology of the cell 22, 1529-38. PMID: 21411625

3. Neuber, S. et al. (2015) Cell and tissue research 359, 799-816. PMID: 25501895

4. Giglione, C. et al. (2001) European journal of biochemistry 268, 3275-83. PMID: 11389730

5. Jeulin, C. et al. (2008) American journal of physiology. Lung cellular and molecular physiology 295, L489-96. PMID: 18586953

6. David-Pfeuty, T. et al. (1995) Journal of virology 69, 1699-713. PMID: 7853507

7. Taniyama, Y. et al. (2003) Molecular and cellular biology 23, 8019-29. PMID: 14585963

8. Grano, M. et al. (1996) Proceedings of the National Academy of Sciences of the United States of America 93, 7644-8. PMID: 8755529

9. Li, Z. et al. (2024) Nature communications 15, 1300. PMID: 38346942

10. Miyazaki, T. et al. (2003) The Journal of cell biology 160, 709-18. PMID: 12615910

참고사항

For research use only.

이미지

참고 문헌

데이터시트

Anti-SRC Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-SRC Polyclonal Antibody (HY387014)

개요

이미지

참고 문헌

데이터시트

SDS

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