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| 카탈로그 번호 | HW748014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-SREBF1/SREBP1 Polyclonal Antibody (HW748014) is a rabbit polyclonal antibody detecting SREBF1 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human SREBF1/SREBP1 (Glu30-Leu490). | ||||||||
| 타겟 | Sterol regulatory element-binding protein 1, SREBF1, BHLHD1, Transcription factor SREBF1, Sterol regulatory element-binding transcription factor 1, Class D basic helix-loop-helix protein 1, bHLHd1, SREBP-1, SREBP1 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P36956 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Sterol regulatory element-binding protein 1 (SREBF1/SREBP1) is a ~121 kDa protein. Precursor of the transcription factor form (Processed sterol regulatory element-binding protein 1), which is embedded in the endoplasmic reticulum membrane. Low sterol concentrations promote processing of this form, releasing the transcription factor form that translocates into the nucleus and activates transcription of genes involved in cholesterol biosynthesis and lipid homeostasis. 1. Xu, D. et al. (2020) Nature 580, 530-535. PMID: 32322062 | ||||||||
| 참고사항 | For research use only. |
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