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| 카탈로그 번호 | JN998053 | ||||
|---|---|---|---|---|---|
| 종 반응성 | Staphylococcus aureus | ||||
| 응용 분야 | ELISA, Neutralization, SPR | ||||
| 숙주 종 | Mouse | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG2a | ||||
| 클론 ID | QD20 | ||||
| 타겟 | hly, hla, Alpha-hemolysin, Alpha-toxin, Alpha-HL, AT, Staphylococcus aureus, Staphylococcus aureus (strain NCTC 8325 / PS 47) | ||||
| 내독소 수준 | Please contact with the lab for this information. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | P09616, Q2G1X0 | ||||
| RRID | Anti-Staphylococcus aureus Alpha-toxin/hly/AT Antibody (QD20) (abinScience Cat# JN998053, RRID:AB_3729029) |
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| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 배경 | Alpha-hemolysin (Alpha-toxin/hly) is a ~35 kDa protein. Alpha-toxin binds to the membrane of eukaryotic cells (particularly red blood cells, RBC) forming pores, resulting in hemolysis, with the release of low-molecular weight molecules leading to eventual osmotic RBC lysis. Human RBCs bind much less alpha-toxin than do rabbit RBCs. Heptamer oligomerization and pore formation is required for lytic activity. 1. Walker, B. et al. (1992) The Journal of biological chemistry 267, 10902-9. PMID: 1587866 2. Wilke, GA. et al. (2010) Proceedings of the National Academy of Sciences of the United States of America 107, 13473-8. PMID: 20624979 | ||||
| 참고사항 | For research use only. |
SDS-PAGE for Anti-Staphylococcus aureus Alpha-toxin/hly/AT Antibody (QD20)
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중국 우한시 심둔사로 666번지 C동, 우한, 430206
