Anti-SUMF1 Polyclonal Antibody (HV152014)

Name: Anti-SUMF1 Polyclonal Antibody
Brand: abinScience
SKU: HV152014
Price: 168 USD
Availability: InStock

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100ug

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개요
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개요

카탈로그 번호

HV152014

설명

Anti-SUMF1 Polyclonal Antibody (HV152014) is a rabbit polyclonal antibody detecting SUMF1 in ELISA, IHC, WB. Suitable for Bovine, Human, and Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant Human SUMF1 (Glu113-Ser356).

타겟

Formylglycine-generating enzyme, FGE, SUMF1, Sulfatase-modifying factor 1, C-alpha-formylglycine-generating enzyme 1

정제

Purified by antigen affinity column.

등록번호

Q8NBK3

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Formylglycine-generating enzyme (SUMF1) is a ~40 kDa protein. Oxidase that catalyzes the conversion of cysteine to 3-oxoalanine on target proteins, using molecular oxygen and an unidentified reducing agent. 3-oxoalanine modification, which is also named formylglycine (fGly), occurs in the maturation of arylsulfatases and some alkaline phosphatases that use the hydrated form of 3-oxoalanine as a catalytic nucleophile. Known substrates include GALNS, ARSA, STS and ARSE.

1. Cosma, MP. et al. (2003) Cell 113, 445-56. PMID: 12757706

2. Preusser-Kunze, A. et al. (2005) The Journal of biological chemistry 280, 14900-10. PMID: 15657036

3. Dierks, T. et al. (2005) Cell 121, 541-552. PMID: 15907468

4. Roeser, D. et al. (2006) Proceedings of the National Academy of Sciences of the United States of America 103, 81-6. PMID: 16368756

5. Schlotawa, L. et al. (2011) European journal of human genetics : EJHG 19, 253-61. PMID: 21224894

6. Holder, PG. et al. (2015) The Journal of biological chemistry 290, 15730-15745. PMID: 25931126

참고사항

For research use only.

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참고 문헌

데이터시트

Anti-SUMF1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-SUMF1 Polyclonal Antibody (HV152014)

개요

이미지

참고 문헌

데이터시트

SDS