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| 카탈로그 번호 | HV242014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-SYTL2 Polyclonal Antibody (HV242014) is a rabbit polyclonal antibody detecting SYTL2 in ELISA, IHC, WB. Suitable for Human, Mouse, and Bovine.
Highlights
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| 종 반응성 | Human, Mouse | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human SYTL2 (Met559-Leu880). | ||||||||
| 타겟 | Breast cancer-associated antigen SGA-72M, SYTL2, Synaptotagmin-like protein 2, SGA72M, SLP2, Exophilin-4, SLP2A, KIAA1597 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q9HCH5 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Synaptotagmin-like protein 2 (SYTL2) is a ~104 kDa protein. Isoform 1 acts as a RAB27A effector protein and plays a role in cytotoxic granule exocytosis in lymphocytes. It is required for cytotoxic granule docking at the immunologic synapse. Isoform 4 binds phosphatidylserine (PS) and phosphatidylinositol-4,5-bisphosphate (PIP2) and promotes the recruitment of glucagon-containing granules to the cell membrane in pancreatic alpha cells. Binding to PS is inhibited by Ca(2+) while binding to PIP2 is Ca(2+) insensitive. | ||||||||
| 참고사항 | For research use only. |
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