

| 카탈로그 번호 | HT202014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-TBX3 Polyclonal Antibody (HT202014) is a rabbit polyclonal antibody detecting TBX3 in ELISA, IHC, WB. Suitable for Mouse, Dog, Danio rerio, Chicken, and Human.
Highlights
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| 종 반응성 | Human, Mouse, Rat | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human TBX3 (Leu107-Thr220). | ||||||||
| 타겟 | TBX3, T-box transcription factor TBX3, T-box protein 3 | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | O15119 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | T-box transcription factor TBX3 is a ~79 kDa protein. Transcriptional repressor involved in developmental processes. Binds to the palindromic T site 5'-TTCACACCTAGGTGTGAA-3' DNA sequence, or a half-site, which are present in the regulatory region of several genes. Probably plays a role in limb pattern formation. Required for mammary placode induction, and maintenance of the mammary buds during development. Involved in branching morphogenesis in both developing lungs and adult mammary glands, via negative modulation of target genes; acting redundantly with TBX2. 1. He, Ml. et al. (1999) Proceedings of the National Academy of Sciences of the United States of America 96, 10212-7. PMID: 10468588 2. Lingbeek, ME. et al. (2002) The Journal of biological chemistry 277, 26120-7. PMID: 12000749 3. Martin, N. et al. (2012) The EMBO journal 31, 95-109. PMID: 22002537 | ||||||||
| 참고사항 | For research use only. |

Western blot analysis was performed using anti-IBX3 polyclonal antibody at 1ug/mL on various samples.
Lane 1: Mouse lung lysate
Lane 2: Rat lung lysate


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