Anti-TCF7 Polyclonal Antibody (HW608024)

Name: Anti-TCF7 Polyclonal Antibody
Brand: abinScience
SKU: HW608024
Price: 168 USD
Availability: InStock

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100ug

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개요
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개요

카탈로그 번호

HW608024

설명

Anti-TCF7 Polyclonal Antibody (HW608024) is a rabbit polyclonal antibody detecting Transcription factor 7; TCF-7; T-cell-specific transcription factor 1; T-cell factor 1; TCF-1; TCF7; TCF1 in ELISA, IHC, WB. Suitable for Mouse, Human, Zebrafish, Frog, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant human TCF7 (Lys270-Glu355).

타겟

Transcription factor 7; TCF-7; T-cell-specific transcription factor 1; T-cell factor 1; TCF-1; TCF7; TCF1

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

Q00417, P36402, Q9NQB0, Q924A0, Q9YHE8, P70063, P70062, Q90ZB6, Q800Q5, P70064, P27782, Q9QXN1, Q9UJU2, Q9HCS4, Q9Z1J1, Q8IMA8, P91943

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Transcription factor 7 (TCF7) is a ~45 kDa protein. Transcriptional activator involved in T-cell lymphocyte differentiation. Necessary for the survival of CD4(+) CD8(+) immature thymocytes. Isoforms lacking the N-terminal CTNNB1 binding domain cannot fulfill this role. Binds to the T-lymphocyte-specific enhancer element (5'-WWCAAAG-3') found in the promoter of the CD3E gene. Represses expression of the T-cell receptor gamma gene in alpha-beta T-cell lineages.

1. Melichar, HJ. et al. (2007) Science (New York, N.Y.) 315, 230-3. PMID: 17218525

2. Malhotra, N. et al. (2013) Immunity 38, 681-93. PMID: 23562159

3. Spidale, NA. et al. (2018) Immunity 49, 857-872.e5. PMID: 30413363

참고사항

For research use only

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참고 문헌

데이터시트

Anti-TCF7 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-TCF7 Polyclonal Antibody (HW608024)

개요

이미지

참고 문헌

데이터시트

SDS