

| 카탈로그 번호 | HW432014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-THOP1 Polyclonal Antibody (HW432014) is a rabbit polyclonal antibody detecting THOP1 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Pig.
Highlights
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| 종 반응성 | Human, Mouse | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human THOP1 (Asn451-Thr597). | ||||||||
| 타겟 | Thimet oligopeptidase, THOP1, MP78, Endopeptidase 24.15 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P52888 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Thimet oligopeptidase (THOP1) is a ~78 kDa protein. Involved in the metabolism of neuropeptides under 20 amino acid residues long. Involved in cytoplasmic peptide degradation. Able to degrade the amyloid-beta precursor protein and generate amyloidogenic fragments. Also acts as a regulator of cannabinoid signaling pathway by mediating degradation of hemopressin, an antagonist peptide of the cannabinoid receptor CNR1. 1. Lim, EJ. et al. (2007) The Journal of biological chemistry 282, 9722-9732. PMID: 17251185 2. Thompson, A. et al. (1995) Biochemical and biophysical research communications 213, 66-73. PMID: 7639763 | ||||||||
| 참고사항 | For research use only. |
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