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| 카탈로그 번호 | AY583024 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Tocilizumab Polyclonal Antibody (AY583024) is a rabbit polyclonal antibody detecting Tocilizumab in ELISA.
Highlights
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| 종 반응성 | General | ||||||||
| 응용 분야 | ELISA | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | Tocilizumab | ||||||||
| 타겟 | Rabbit polyclonal to Actemra. | ||||||||
| 특이성 | The product is specific for Tocilizumab. This antibody serves as an excellent positive control for Tocilizumab immunogenicity (ADA) assays. | ||||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||||
| 순도 | >90% as determined by SDS-PAGE. | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | CAS: 375823-41-9 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Tocilizumab (Actemra) is a humanized monoclonal antibody that is developed by Hoffmann–La Roche and Chugai for the treatment of patients with rheumatoid arthritis (RA) and systemic juvenile idiopathic arthritis, a severe form of arthritis in children. Tocilizumab binds to the interleukin-6 receptor (IL-6R) and blocks its interaction with interleukin 6 (IL-6), hindering IL-6 from exerting its pro-inflammatory effects. • Evaluation of a biosensor immunoassay for simultaneous characterization of isotype and binding region of human anti-tocilizumab antibodies with control by surrogate standards., PMID:19379704 | ||||||||
| 참고사항 | For research use only. |
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