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| 카탈로그 번호 | JN902013 | ||||
|---|---|---|---|---|---|
| 종 반응성 | Toxoplasma gondii | ||||
| 응용 분야 | ELISA, WB | ||||
| 숙주 종 | Human | ||||
| 클론성 | Monoclonal | ||||
| 이소타입 | IgG1 | ||||
| 클론 ID | SAA2154 | ||||
| 타겟 | Major surface antigen p30 | ||||
| 내독소 수준 | Please contact with the lab for this information. | ||||
| 순도 | >95% as determined by SDS-PAGE. | ||||
| 정제 | Protein A/G purified from cell culture supernatant. | ||||
| 등록번호 | P13664 | ||||
| RRID | Anti-Toxoplasma gondii SAG1/Major surface antigen p30 Antibody (SAA2154) (abinScience Cat# JN902013, RRID:AB_3729523) |
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| 형태 | Liquid | ||||
| 저장 완충액 | 0.01M PBS pH 7.4 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. | ||||
| 배경 | Major surface antigen p30 (SAG1) is a ~34 kDa protein. Mediates binding to host cells and is especially important for parasite attachment and fitness in IFN-gamma/IFNG-stimulated host cells. May regulate binding between human S100A6 and vimentin (VIM) for cytoskeleton organization during the early stages of invasion into host cells. Promotes TNF secretion in host cells probably by enhancing binding between human VIM and PRKCQ and activating NF-kappa-B pathway. Promotes viability of host cells to satisfy the survival needs of parasites through the interaction with human RACK1. 1. Robinson, SA. et al. (2004) Parasitology 128, 391-6. PMID: 15151144 2. Cohen, O. et al. (2025) Infection and immunity 93, e0001025. PMID: 40607979 3. Zhou, LJ. et al. (2021) iScience 24, 103514. PMID: 34950858 4. Wang, D. et al. (2024) Acta tropica 251, 107112. PMID: 38157925 | ||||
| 참고사항 | For research use only. |
SDS-PAGE for Anti-Toxoplasma gondii SAG1/Major surface antigen p30 Recombinant Antibody (SAA2154)
Western blot analysis was performed using anti-/ monoclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant Toxoplasma gondii SAG1/Major surface antigen p30(Catalog No: JN902012)
Lane 2: negative control
Lane 3: negative control
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