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| 카탈로그 번호 | JN038014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-Treponema pallidum TPP47 Polyclonal Antibody (JN038014) is a rabbit polyclonal antibody detecting Treponema Pallidum (TP in ELISA, IHC, WB.
Highlights
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| 종 반응성 | Treponema pallidum | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Treponema pallidum TPP47 (Cys20-Gln434). | ||||||||
| 타겟 | Putative DD-carboxypeptidase TP_0574, 3.4.-.-, 47 kDa lipoprotein, Tp47, Tpp47, 47 kDa membrane antigen, 47-kilodalton major integral membrane immunogen, TP_0574, Treponema Pallidum (TP, Syphilis) | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P29723 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Putative DD-carboxypeptidase TP_0574 (TPP47) is a ~47 kDa protein. A possible D,D-carboxypeptidase, that releases amino acids sequentially from a proteins C-terminus. Has zinc-dependent carboxypeptidase activity on synthetic depsipeptide substrates. May serve to decrease cross-linking of peptidoglycan, promoting the highly sinusous motility of this spirochaete (Probable). Overexpression of the whole protein in E.coli leads to aberrant cell morphology and extrusion of the cytoplasm, while overexpression of a construct with the first 62 resides of the protein fused to PhoA does have this effect, suggesting the whole protein, not the lipoprotein moiety, is toxic. Binds penicillin. 1. Deka, RK. et al. (2002) The Journal of biological chemistry 277, 41857-64. PMID: 12196546 2. Weigel, LM. et al. (1994) Proceedings of the National Academy of Sciences of the United States of America 91, 11611-5. PMID: 7972112 3. Radolf, JD. et al. (1989) Infection and immunity 57, 1248-54. PMID: 2647634 | ||||||||
| 참고사항 | For research use only. |
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