

| 카탈로그 번호 | HV333014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-TRPC6 Polyclonal Antibody (HV333014) is a rabbit polyclonal antibody detecting TRPC6 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human TRPC6 (Met1-Leu192). | ||||||||
| 타겟 | TrpC6, TRP-6, Short transient receptor potential channel 6, Transient receptor protein 6, TRP6, TRPC6 | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | Q9Y210 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Short transient receptor potential channel 6 (TRPC6) is a ~106 kDa protein. Forms a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) in a membrane-delimited fashion, independently of protein kinase C. Does not seem to be activated by intracellular calcium store depletion. 1. Heeringa, SF. et al. (2009) PloS one 4, e7771. PMID: 19936226 2. Hofstra, JM. et al. (2013) Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 28, 1830-8. PMID: 23291369 3. Riehle, M. et al. (2016) Journal of the American Society of Nephrology : JASN 27, 2771-83. PMID: 26892346 4. Hofmann, T. et al. (1999) Nature 397, 259-63. PMID: 9930701 | ||||||||
| 참고사항 | For research use only. |
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