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| 카탈로그 번호 | HY155014 | ||||||
|---|---|---|---|---|---|---|---|
| 설명 |
Anti-TXN Polyclonal Antibody (HY155014) is a rabbit polyclonal antibody detecting TXN in ELISA, IHC, WB. Suitable for Human.
Highlights
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| 종 반응성 | Human | ||||||
| 응용 분야 | ELISA, IHC, WB | ||||||
| 숙주 종 | Rabbit | ||||||
| 클론성 | Polyclonal | ||||||
| 이소타입 | IgG | ||||||
| 면역원 | E. coli - derived recombinant Human TXN (Val2-Val105). | ||||||
| 타겟 | Trx, TXN, TRX1, SASP, Hom s Trx, Thioredoxin, ATL-derived factor, ADF, TRX, Surface-associated sulphydryl protein, TRDX | ||||||
| 내독소 수준 | Please contact with the lab for this information. | ||||||
| 정제 | Purified by antigen affinity column. | ||||||
| 등록번호 | P10599 | ||||||
| 형태 | Liquid | ||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 재구성 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. | ||||||
| 배송 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. | ||||||
| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||
| 배경 | Thioredoxin (TXN) is a ~11 kDa protein. Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity. 1. Limacher, A. et al. (2007) Journal of immunology (Baltimore, Md. : 1950) 178, 389-96. PMID: 17182577 2. Glaser, AG. et al. (2008) Allergy 63, 1617-23. PMID: 19032234 3. Jacquot, JP. et al. (1990) Biochemical and biophysical research communications 173, 1375-81. PMID: 2176490 4. Mitchell, DA. et al. (2005) Nature chemical biology 1, 154-8. PMID: 16408020 5. Mitchell, DA. et al. (2007) Proceedings of the National Academy of Sciences of the United States of America 104, 11609-14. PMID: 17606900 6. Wei, SJ. et al. (2000) Cancer research 60, 6688-95. PMID: 11118054 7. Hirota, K. et al. (1997) Proceedings of the National Academy of Sciences of the United States of America 94, 3633-8. PMID: 9108029 | ||||||
| 참고사항 | For research use only. |
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