Anti-UBE2N Polyclonal Antibody (HB321014)

Name: Anti-UBE2N Polyclonal Antibody
Brand: abinScience
SKU: HB321014
Price: 96 USD
Availability: InStock

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개요
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SDS

개요

카탈로그 번호

HB321014

설명

Anti-UBE2N Polyclonal Antibody (HB321014) is a rabbit polyclonal antibody detecting Ubiquitin-conjugating enzyme E2 N; 2.3.2.23; Bendless-like ubiquitin-conjugating enzyme; E2 ubiquitin-conjugating enzyme N; Ubc13; UbcH13; Ubiquitin carrier protein N; Ubiquitin-protein ligase N; UBE2N; BLU in ELISA, IHC, WB. Suitable for Human, Bovine, Mouse, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant human UBE2N (Met1-Ile152).

타겟

Ubiquitin-conjugating enzyme E2 N; 2.3.2.23; Bendless-like ubiquitin-conjugating enzyme; E2 ubiquitin-conjugating enzyme N; Ubc13; UbcH13; Ubiquitin carrier protein N; Ubiquitin-protein ligase N; UBE2N; BLU

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

P61088, Q0P5K3, P61089, Q9EQX9, Q5JXB2, Q95XX0

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Ubiquitin-conjugating enzyme E2 N (UBE2N) is a ~17 kDa protein. The UBE2V1-UBE2N and UBE2V2-UBE2N heterodimers catalyze the synthesis of non-canonical 'Lys-63'-linked polyubiquitin chains. This type of polyubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.

1. Shi, Y. et al. (2017) Nature communications 8, 15138. PMID: 28469175

2. Cadena, C. et al. (2019) Cell 177, 1187-1200.e16. PMID: 31006531

참고사항

For research use only

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참고 문헌

데이터시트

Anti-UBE2N Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-UBE2N Polyclonal Antibody (HB321014)

개요

이미지

참고 문헌

데이터시트

SDS