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Anti-UBXN2B Polyclonal Antibody (HB411014)

Anti-UBXN2B Polyclonal Antibody
Anti-UBXN2B Polyclonal Antibody
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  • 개요

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개요
카탈로그 번호HB411014
설명
Anti-UBXN2B Polyclonal Antibody (HB411014) is a rabbit polyclonal antibody detecting UBX domain-containing protein 2B; NSFL1 cofactor p37; p97 cofactor p37; UBXN2B in ELISA, IHC, WB. Suitable for Human, Rat, and Mouse.
Highlights
  • ●Affinity Purified — Minimal background and high purity for reliable results.
  • ●Multi-Application — Validated across multiple applications.
  • ●Multi-Species — Cross-reactive for translational research.
종 반응성Human
응용 분야ELISA, IHC, WB
숙주 종Rabbit
클론성Polyclonal
이소타입IgG
면역원 E. coli - derived recombinant human UBXN2B (Leu244-Lys331).
타겟 UBX domain-containing protein 2B; NSFL1 cofactor p37; p97 cofactor p37; UBXN2B
내독소 수준 Please contact with the lab for this information.
정제 Purified by antigen affinity column.
등록번호 Q14CS0, P0C627, Q0KL01
형태 Liquid
저장 완충액 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보
응용 분야 희석
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
안정성 및 저장 Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
배경

UBX domain-containing protein 2B (UBXN2B) is a ~37 kDa protein. Adapter protein required for Golgi and endoplasmic reticulum biogenesis. Involved in Golgi and endoplasmic reticulum maintenance during interphase and in their reassembly at the end of mitosis. The complex formed with VCP has membrane fusion activity; membrane fusion activity requires USO1-GOLGA2 tethering and BET1L. VCPIP1 is also required, but not its deubiquitinating activity. Together with NSFL1C/p47, regulates the centrosomal levels of kinase AURKA/Aurora A during mitotic progression by promoting AURKA removal from centrosomes in prophase.

1. Uchiyama, K. et al. (2006) Developmental cell 11, 803-16. PMID: 17141156
2. Kress, E. et al. (2013) The Journal of cell biology 201, 559-75. PMID: 23649807
참고사항 For research use only
이미지
  • Anti-UBXN2B Polyclonal Antibody

    Western blot

    Lane 1: A549 cell lysate

참고 문헌
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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