Anti-UFM1 Polyclonal Antibody (HB333014)

Name: Anti-UFM1 Polyclonal Antibody
Brand: abinScience
SKU: HB333014
Price: 168 USD
Availability: InStock

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HB333014

설명

Anti-UFM1 Polyclonal Antibody (HB333014) is a rabbit polyclonal antibody detecting Ubiquitin-fold modifier 1; UFM1; C13orf20; BM-002 in ELISA, IHC, WB. Suitable for Human, Mouse, Bovine, Rat, and Zebrafish.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant human UFM1 (Ser2-Gly83).

타겟

Ubiquitin-fold modifier 1; UFM1; C13orf20; BM-002

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

P61960, P61961, Q2KJG2, Q5BJP3, Q803Y4, Q5ZMK7, Q5RJW4, B5LVL2, P34661, A8DYH2, Q9CA23

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Ubiquitin-fold modifier 1 (UFM1) is a ~9 kDa protein. Ubiquitin-like modifier which can be covalently attached via an isopeptide bond to lysine residues of substrate proteins as a monomer or a lysine-linked polymer. The so-called ufmylation, requires the UFM1-activating E1 enzyme UBA5, the UFM1-conjugating E2 enzyme UFC1, and the UFM1-ligase E3 enzyme UFL1. Ufmylation is involved in various processes, such as ribosome recycling, response to DNA damage, transcription or reticulophagy (also called ER-phagy) induced in response to endoplasmic reticulum stress.

1. Komatsu, M. et al. (2004) The EMBO journal 23, 1977-86. PMID: 15071506

2. Tatsumi, K. et al. (2010) The Journal of biological chemistry 285, 5417-27. PMID: 20018847

3. Oweis, W. et al. (2016) Cell reports 16, 3113-3120. PMID: 27653677

4. Nahorski, MS. et al. (2018) Brain : a journal of neurology 141, 1934-1945. PMID: 29868776

5. Walczak, CP. et al. (2019) Proceedings of the National Academy of Sciences of the United States of America 116, 1299-1308. PMID: 30626644

6. He, C. et al. (2024) Molecular cell 84, 1120-1138.e8. PMID: 38377992

7. DaRosa, PA. et al. (2024) Nature 627, 445-452. PMID: 38383785

8. Yoo, HM. et al. (2014) Molecular cell 56, 261-274. PMID: 25219498

9. Liang, JR. et al. (2020) Cell 180, 1160-1177.e20. PMID: 32160526

참고사항

For research use only

이미지

참고 문헌

데이터시트

Anti-UFM1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-UFM1 Polyclonal Antibody (HB333014)

개요

이미지

참고 문헌

데이터시트

SDS

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