

| 카탈로그 번호 | HY032014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| 설명 |
Anti-UMOD Polyclonal Antibody (HY032014) is a rabbit polyclonal antibody detecting UMOD in ELISA, IHC, WB. Suitable for Human, Dog, Bovine, and Pongo abelii.
Highlights
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| 종 반응성 | Human | ||||||||
| 응용 분야 | ELISA, IHC, WB | ||||||||
| 숙주 종 | Rabbit | ||||||||
| 클론성 | Polyclonal | ||||||||
| 이소타입 | IgG | ||||||||
| 면역원 | E. coli - derived recombinant Human UMOD (Glu334-Ser589). | ||||||||
| 타겟 | Tamm-Horsfall urinary glycoprotein, THP, Uromodulin, UMOD | ||||||||
| 정제 | Purified by antigen affinity column. | ||||||||
| 등록번호 | P07911 | ||||||||
| 형태 | Liquid | ||||||||
| 저장 완충액 | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요. |
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| 제품 사용 정보 |
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| 안정성 및 저장 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| 배경 | Uromodulin (UMOD) is a ~69 kDa protein. Functions in biogenesis and organization of the apical membrane of epithelial cells of the thick ascending limb of Henle's loop (TALH), where it promotes formation of complex filamentous gel-like structure that may play a role in the water barrier permeability (Probable). May serve as a receptor for binding and endocytosis of cytokines (IL-1, IL-2) and TNF. Facilitates neutrophil migration across renal epithelia. 1. Hession, C. et al. (1987) Science (New York, N.Y.) 237, 1479-84. PMID: 3498215 2. Schmid, M. et al. (2010) Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 26, 311-8. PMID: 20798515 | ||||||||
| 참고사항 | For research use only. |
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