Anti-VPS26A Polyclonal Antibody (HB599014)

Name: Anti-VPS26A Polyclonal Antibody
Brand: abinScience
SKU: HB599014
Price: 168 USD
Availability: InStock

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100ug

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개요
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참고 문헌
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SDS

개요

카탈로그 번호

HB599014

설명

Anti-VPS26A Polyclonal Antibody (HB599014) is a rabbit polyclonal antibody detecting Vacuolar protein sorting-associated protein 26A; Vesicle protein sorting 26A; hVPS26; VPS26A; VPS26 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Bovine, and Frog.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

종 반응성

Human, Mouse, Rat

응용 분야

ELISA, IHC, WB

숙주 종

Rabbit

클론성

Polyclonal

이소타입

IgG

면역원

E. coli - derived recombinant human VPS26A (Met1-Gln305).

타겟

Vacuolar protein sorting-associated protein 26A; Vesicle protein sorting 26A; hVPS26; VPS26A; VPS26

내독소 수준

Please contact with the lab for this information.

정제

Purified by antigen affinity column.

등록번호

O75436, P40336, Q6AY86, Q0VD53, Q6DFU4, Q6IRD0, Q6TNP8

형태

Liquid

저장 완충액

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.

제품 사용 정보

응용 분야	희석
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

안정성 및 저장

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

배경

Vacuolar protein sorting-associated protein 26A (VPS26A) is a ~38 kDa protein. Acts as a component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX3-retromer mediates the retrograde endosome-to-TGN transport of WLS distinct from the SNX-BAR retromer pathway.

1. Seaman, MN. (2004) The Journal of cell biology 165, 111-22. PMID: 15078902

2. Arighi, CN. et al. (2004) The Journal of cell biology 165, 123-33. PMID: 15078903

3. Vergés, M. et al. (2004) Nature cell biology 6, 763-9. PMID: 15247922

4. Harbour, ME. et al. (2012) The Biochemical journal 442, 209-20. PMID: 22070227

5. Harbour, ME. et al. (2010) Journal of cell science 123, 3703-17. PMID: 20923837

6. Fjorback, AW. et al. (2012) The Journal of neuroscience : the official journal of the Society for Neuroscience 32, 1467-80. PMID: 22279231

7. Gullapalli, A. et al. (2006) Molecular biology of the cell 17, 1228-38. PMID: 16407403

8. Temkin, P. et al. (2011) Nature cell biology 13, 715-21. PMID: 21602791

참고사항

For research use only

이미지

참고 문헌

데이터시트

Anti-VPS26A Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

재조합 단백질

항체

어세이 키트

Anti-VPS26A Polyclonal Antibody (HB599014)

개요

이미지

참고 문헌

데이터시트

SDS